KNG1 Antikörper

Produktnummer ABIN318367

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch KNG1 in EIA. Er zeigt eine Reaktivität gegenüber Human und Vicia faba.

Kurzübersicht für KNG1 Antikörper (ABIN318367)

Target: KNG1 (Kininogen 1 (KNG1))

Reaktivität: Human, Vicia faba

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser KNG1 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Produktdetails anti-KNG1 Antikörper

Sequenz: RPPGFSPFR

Spezifität: This antibody is specific for Bradykinin and Lys-Bradykinin (kallidin).

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Bradykinin peptide conjugated to c.BSA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 5.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KNG1

Target: KNG1 (Kininogen 1 (KNG1))

Andere Bezeichnung: Kininogen-1

Hintergrund: Bradykinin is a nine amino acid vasoactive peptide which elicits numerous physiologic responses such as vasodilation, smooth muscle spasm and pain. Bradykinin is one of a family of such peptides called the kinins. These kinins are generated by proteolysis of high molecular weight precursors called kininogens upon activation by pathophysiologic conditions such as inflammation or allergy. The physiological actions of these kinins are brought about through their interaction with transmembrane receptors. There are two distinct bradykinin receptor subtypes, B1 and B2, both of which appear to be coupled to G-proteins. The B2 receptor subtype is found in healthy smooth muscle cells and neurons, whereas the B1 receptors are only detected following tissue injury. The B2 receptor is similar in structure to other seven helix G protein coupled receptors. Bradykinin has relatively low affinity for B1 receptors, interacting primarily with the B2 receptor through which several second messenger systems are stimulated, including inositol phospholipid hydrolysis, arachidonic acid metabolism, tyrosine phosphorylation, and membrane depolarization and hyperpolarization.Synonyms: Bradykinin, Kallidin-1, Kallidin-I, Kallidin1

Gen-ID: 3827

NCBI Accession: NP_000884

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process