CPN1 Antikörper
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- Target Alle CPN1 Antikörper anzeigen
- CPN1 (Carboxypeptidase N Subunit 1 (CPN1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CPN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- CPN cat antibody detects endogenous levels of CPN cat protein.(region surrounding Gln452)
- Aufreinigung
- Affinity chromatography
- Top Product
- Discover our top product CPN1 Primärantikörper
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- Applikationshinweise
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CPN1 (Carboxypeptidase N Subunit 1 (CPN1))
- Andere Bezeichnung
- Carboxypeptidase N Catalytic Chain (CPN1 Produkte)
- Synonyme
- CPN antikoerper, SCPN antikoerper, Cpn antikoerper, cb1037 antikoerper, fa99g08 antikoerper, wu:fa99g08 antikoerper, zgc:77485 antikoerper, cpn antikoerper, scpn antikoerper, 0610011F20Rik antikoerper, carboxypeptidase N subunit 1 antikoerper, carboxypeptidase N, polypeptide 1 antikoerper, carboxypeptidase N subunit 1 S homeolog antikoerper, CPN1 antikoerper, Cpn1 antikoerper, cpn1 antikoerper, cpn1.S antikoerper
- Hintergrund
- Carboxypeptidase N (arginine carboxypeptidase or CPN) cleaves basic amino acid residues from the carboxy terminal of peptides and proteins. The enzyme plays a central role in regulating the biologic activity of peptides such as kinins and anaphylatoxins, and therefore is also known as kininase-1 and anaphylatoxin inactivator. CPN is a tetrameric complex consisting of two identical regulatory subunits (CPN reg) and two identical catalytic subunits (CPN cat). The two glycosylated CPN reg subunits protect the two CPN cat subunits and keep them in the circulation. CPN reg is a member of the leucinerich repeat family of proteins and the gene which encodes CPN reg maps to human chromosome 8p22-p23. CPN cat is a member of the regulatory B-type carboxypeptidase group and the gene which encodes CPN cat maps to human chromosome 10.Synonyms: ACBP, Anaphylatoxin inactivator, Arginine carboxypeptidase, CPN, CPN1, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, SCPN, Serum carboxypeptidase N
- Molekulargewicht
- approx. 52 kDa
- Gen-ID
- 1369
- NCBI Accession
- NP_001299
- UniProt
- P15169
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process
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