SSTR4 Antikörper

Produktnummer ABIN317867

Der Kaninchen Polyklonal anti-SSTR4 Antikörper wird verwendet zum Nachweis von SSTR4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für SSTR4 Antikörper (ABIN317867)

Target: SSTR4 (Somatostatin Receptor 4 (SSTR4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSTR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SSTR4 Antikörper

Spezifität: SSTR4 antibody detects endogenous levels of SSTR4 protein.(region surrounding Gln194)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SSTR4

Target: SSTR4 (Somatostatin Receptor 4 (SSTR4))

Andere Bezeichnung: SSTR4

Hintergrund: SSTRs (for somatostatin receptors) represent a family of G-protein-coupled receptors which mediate the diverse biological actions of somatostatin(SST). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28. SSTR2 gives rise to spliced variants, SSTR2A and 2B. SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins. Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4). Individual target cells typically express more than one SSTR subtype and often all five isoforms. Subtypes of SSTR can form functional homo- and heterodimers.Synonyms: SS-4-R, SS4-R, SS4R, Somatostatin receptor type 4

Molekulargewicht: approx. 42 kDa

Gen-ID: 6754

NCBI Accession: NP_001043

UniProt: P31391

Pathways: cAMP Metabolic Process