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FZD2 Antikörper

FZD2 Reaktivität: Human, Ratte, Maus WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN317860
  • Target Alle FZD2 Antikörper anzeigen
    FZD2 (Frizzled Family Receptor 2 (FZD2))
    Reaktivität
    • 43
    • 18
    • 15
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 41
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 43
    • 3
    Polyklonal
    Konjugat
    • 28
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FZD2 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 22
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Spezifität
    This antibody detects endogenous levels of Frizzled-2 protein.(region surrounding Glu240)
    Aufreinigung
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product FZD2 Primärantikörper
  • Applikationshinweise
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    FZD2 (Frizzled Family Receptor 2 (FZD2))
    Andere Bezeichnung
    FZD2 / Frizzled-2 (FZD2 Produkte)
    Synonyme
    BG01711 antikoerper, CG9739 antikoerper, D-Fz2 antikoerper, D-fz2 antikoerper, DFZ2 antikoerper, DFz-2 antikoerper, DFz2 antikoerper, Dfrz2 antikoerper, Dfz2 antikoerper, Dfz[[2]] antikoerper, Dm Fz2 antikoerper, Dmel\\CG9739 antikoerper, FZ2 antikoerper, Fz2 antikoerper, dFz2 antikoerper, dfz(2) antikoerper, dfz2 antikoerper, dfz2r antikoerper, frz2 antikoerper, fz-2 antikoerper, fz8 antikoerper, zfz2 antikoerper, zg08 antikoerper, cb383 antikoerper, wu:fb70g09 antikoerper, FZD2 antikoerper, fzE2 antikoerper, hFz2 antikoerper, Fz-10 antikoerper, Fzd10 antikoerper, cFz-2 antikoerper, frizzled2 antikoerper, fz2 antikoerper, xfz2 antikoerper, AL033370 antikoerper, AW456835 antikoerper, Fz10 antikoerper, Mfz10 antikoerper, Mfz10a antikoerper, frizzled 2 antikoerper, frizzled class receptor 2 antikoerper, frizzled class receptor 2 S homeolog antikoerper, fz2 antikoerper, fzd2 antikoerper, FZD2 antikoerper, Fzd2 antikoerper, fzd2.S antikoerper
    Hintergrund
    The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy-terminal Ser/Thr-XXX-Val motif. The proteins in this family function as receptors for Wnt and are generally coupled to G proteins. Frizzleds are members of the G protein-coupled receptor superfamily. Frizzled-2 is expressed in the fetal kidney and lung and in the adult ovary and colon. Frizzled-2 mediates the Wnt/cGMP/Ca2+ pathway. It binds Wnt proteins and signals by activating the release of stored calcium. Frizzled-2 expression is regulated by Angiotensin II. Activated frizzled-2 suppresses the activity of protein kinase G, and activates NFAT-dependent transcription, the phosphatidylinositol pathway and calcium sensitive enzymes.Synonyms: Fz-2, FzE2, hFz2
    Molekulargewicht
    approx. 55 kDa
    Gen-ID
    2535
    NCBI Accession
    NP_001457
    UniProt
    Q14332
    Pathways
    WNT Signalweg
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