CCKBR Antikörper

Produktnummer ABIN317856

Der Kaninchen Polyklonal anti-CCKBR Antikörper (ABIN317856) detektiert spezifisch CCKBR in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CCKBR Antikörper (ABIN317856)

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCKBR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CCKBR Antikörper

Spezifität: This antibody detects endogenous levels of CCK-BR protein.(region surrounding Leu54)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CCKBR

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Andere Bezeichnung: CCK-B Receptor

Hintergrund: CCKBR is a G protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR is most abundant in brain and stomach but it can also be found in colon, pancreas, thyroid, and various cancers.Synonyms: CCK-BR, CCK2-R, CCKB Receptor, CCKBR, CCKRB, Cholecystokinin type B receptor, Cholecystokinin-2 receptor, Gastrin/cholecystokinin type B receptor

Molekulargewicht: approx. 52 kDa

Gen-ID: 887

NCBI Accession: NP_795344

UniProt: P32239

Pathways: Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour