FZD9 Antikörper
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- Target Alle FZD9 Antikörper anzeigen
- FZD9 (Frizzled Family Receptor 9 (FZD9))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FZD9 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Spezifität
- Frizzled-9 antibody detects endogenous levels of Frizzled-9 protein.(region surrounding Leu591)
- Aufreinigung
- Affinity-chromatography
- Top Product
- Discover our top product FZD9 Primärantikörper
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- Applikationshinweise
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FZD9 (Frizzled Family Receptor 9 (FZD9))
- Andere Bezeichnung
- CD349 / FZD9 / Frizzled-9 (FZD9 Produkte)
- Synonyme
- CD349 antikoerper, FZD3 antikoerper, mfz9 antikoerper, Fz-9 antikoerper, cFz-9 antikoerper, fz11 antikoerper, fzd9 antikoerper, fzx antikoerper, hm:zehl0603 antikoerper, zehl0603 antikoerper, zg11 antikoerper, frizzled class receptor 9 antikoerper, frizzled class receptor 9a antikoerper, frizzled class receptor 9b antikoerper, FZD9 antikoerper, Fzd9 antikoerper, fzd9a antikoerper, fzd9b antikoerper
- Hintergrund
- The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled as well as several secreted mammalian frizzled-related proteins (FRPs) have been described. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt and are generally coupled to G proteins. The frizzled-9 gene is located within the Williams Syndrome common deleted region at chromosomal band 7q11.23. Heterozygous deletion of the frizzled-9 gene may contribute to the Williams Syndrome phenotype. In mouse, frizzled-9 overexpression can induce the hyperphosphorylation and relocalization of Dvl-1 from the cytoplasm to the cell membrane and cytosolic β-catenin accumulation. In rat, frizzled-9 is important in Wnt/β-catenin signaling in 293T cells. Frizzled-9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.Synonyms: Fz-9, hFz9
- Molekulargewicht
- approx. 64 kDa
- Gen-ID
- 8326
- NCBI Accession
- NP_003499
- UniProt
- O00144
- Pathways
- WNT Signalweg
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