BRS3 Antikörper

Produktnummer ABIN317729

Der Kaninchen Polyklonal anti-BRS3 Antikörper wird verwendet zum Nachweis von BRS3 in Proben von Human. Er wurde validiert für WB, IF und EIA.

Kurzübersicht für BRS3 Antikörper (ABIN317729)

Target: BRS3 (Bombesin-Like Receptor 3 (BRS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-BRS3 Antikörper

Spezifität: This antibody detects endogenous levels of BRS3 (region surrounding Cys203).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity-chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BRS3

Target: BRS3 (Bombesin-Like Receptor 3 (BRS3))

Andere Bezeichnung: BRS3

Hintergrund: Bombesin receptor subtype-3 (BRS3) is an integral membrane protein belonging to the G protein-coupled receptor 1 family. The gene encoding for the BRS3 protein maps against chromosome Xq26-q28. BRS3 is important in sperm cell division, maturation and function. Its actions are mediated by G protein interactions which activate a phosphatidylinositol-calcium second messenger system. BRS3 is expressed in germ cells in testis and in lung carcinoma cells. Unlike other bombesin proteins, BRS3 does not seem to be detected in the gut and central nervous system, but has been found in rat gastrointestinal tract. Mice lacking the gene encoding for BRS3 develop obesity, suggesting that BRS3 may play a role in the regulation of plasma insulin concentration.Synonyms: BRS-3, Bombesin receptor subtype-3

Molekulargewicht: approx. 44 kDa

Gen-ID: 680

NCBI Accession: NP_001718

UniProt: P32247

Pathways: Feeding Behaviour