PTH1R Antikörper

Produktnummer ABIN317698

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PTH1R in WB, IF, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für PTH1R Antikörper (ABIN317698)

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTH1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PTH1R Antikörper

Spezifität: This antibody detects endogenous levels of PTH/PTHrP-R protein.(region surrounding Leu187)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PTH1R

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Andere Bezeichnung: PTH Receptor 1

Hintergrund: Parathyroid Hormone (PTH), which is also designated parathyrin, is an 84 amino acid single chain peptide that functions to regulate calcium metabolism by raising blood levels of calcium through various mechanisms. PTH stimulates bone formation to increase bone mass and strength in rats and humans. Within the PTH molecule, the essential activity is associated with the first 34 amino acids at the amino-terminus of the molecule. The gene encoding PTH maps to human chromosome 11p15.3-p15.1. Parathyroid hormone-related protein (PTH-rP) is an autocrine factor that is structurally related to PTH yet, unlike PTH, which is synthesized only by the parathyroid cells, PTH-rP is synthesized by several cell types. PTH-rP regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Isolated from the culture medium of a human lung cancer cell line, PTH-rP produces PTH-like effects that are characterized as humoral hypercalcemia of malignancy.Synonyms: PTH/PTHrP type I receptor, PTH1R, PTHR, PTHR1, Parathyroid hormone 1 receptor, Parathyroid hormone/parathyroid hormone-related peptide receptor

Molekulargewicht: approx. 52 kDa

Gen-ID: 5745

NCBI Accession: NP_000307

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process