FZD1 Antikörper
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- Target Alle FZD1 (Fzd1) Antikörper anzeigen
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FZD1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Spezifität
- This antibody detects endogenous levels of Frizzled-1 protein.(region surrounding Leu55)
- Aufreinigung
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product Fzd1 Primärantikörper
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- Applikationshinweise
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ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
- Andere Bezeichnung
- FZD1 / Frizzled-1 (Fzd1 Produkte)
- Synonyme
- CG17697 antikoerper, CG3646 antikoerper, DFZ1 antikoerper, DFz antikoerper, DFz1 antikoerper, Dfz1 antikoerper, Dm Fz1 antikoerper, Dmel\\CG17697 antikoerper, FZ antikoerper, Frz antikoerper, Fz antikoerper, Fz1 antikoerper, frz antikoerper, fz1 antikoerper, fz[[1]] antikoerper, Fz-1 antikoerper, cFz-1 antikoerper, Xfrizzled-1 antikoerper, frizzled1 antikoerper, frz-1 antikoerper, frz1 antikoerper, fzd1-A antikoerper, AW227548 antikoerper, FZ-1 antikoerper, frizzled antikoerper, frizzled class receptor 1 antikoerper, frizzled class receptor 1 L homeolog antikoerper, fz antikoerper, FZD1 antikoerper, Fzd1 antikoerper, fzd1.L antikoerper
- Hintergrund
- The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. The frizzled-1 gene maps to human chromosome 7q21 and is expressed in adult heart, placenta, lung, kidney, pancreas, prostate and ovary and in fetal lung and kidney. Frizzled-2 is expressed in adult heart and fetal brain, lung and kidney. The frizzled related proteins FRP-1, FRP-2, FRP-3, FRP-4 and SARP3 are secreted proteins of approximately 30 kDa that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled and a conserved hydrophilic carboxy terminal.Synonyms: Fz-1, FzE1, hFz1
- Molekulargewicht
- approx. 71 kDa
- Gen-ID
- 8321
- NCBI Accession
- NP_003496
- UniProt
- Q9UP38
- Pathways
- WNT Signalweg, Asymmetric Protein Localization
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