EPH Receptor A2 Antikörper (AA 559-976)
Kurzübersicht für EPH Receptor A2 Antikörper (AA 559-976) (ABIN317513)
Target
Alle EPH Receptor A2 (EPHA2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 559-976
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Spezifität
- The antibody recognizes Human and Mouse EPHA2. Other species not tested.
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Produktmerkmale
- Synonyms: Ephrin type-A receptor 2, Epithelial cell kinase, Eph receptor A2, Tyrosine-protein kinasereceptor ECK
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Aufreinigung
- Protein-G affinity chromatography
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Immunogen
- Recombinant human EphA2 (559-976 aa) purified from E. coli
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Isotyp
- IgG2b
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Applikationshinweise
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ELISA. Western blot (1: 500 - 2,000). Immunohistochemistry (1: 100 - 1: 200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- EPH Receptor A2 (EPHA2)
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Andere Bezeichnung
- EPHA2 / ECK
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Hintergrund
- The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases (RTK). Eph RTKs and their ligands, the ephrins, are frequently overexpressed in a variety of cancers and tumor cell lines. One Eph family member, EphA2, is also overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning and possibly in cancer.Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK
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Gen-ID
- 1969
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UniProt
- P29317
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Pathways
- RTK Signalweg
Target
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