Der Maus Monoklonal anti-EPH Receptor A2 Antikörper wird verwendet zum Nachweis von EPH Receptor A2 in Proben von Human und Maus. Er wurde validiert für WB, IHC (p) und EIA.
ELISA. Western blot (1: 500 - 2,000). Immunohistochemistry (1: 100 - 1: 200). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1.0 mg/mL
Buffer
PBS, pH 7.4, containing 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
EPH Receptor A2 (EPHA2)
Andere Bezeichnung
EPHA2 / ECK
Hintergrund
The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases (RTK). Eph RTKs and their ligands, the ephrins, are frequently overexpressed in a variety of cancers and tumor cell lines. One Eph family member, EphA2, is also overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning and possibly in cancer.Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK