Cathepsin L Antikörper (AA 114-333)

Produktnummer ABIN317508

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Cathepsin L in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für Cathepsin L Antikörper (AA 114-333) (ABIN317508)

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cathepsin L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 2H7

Produktdetails anti-Cathepsin L Antikörper

Bindungsspezifität: AA 114-333

Spezifität: The antibody recognizes Human Cathepsin L. Other species not tested.

Produktmerkmale: Synonyms: CTSL1, CTSL, MEP, Cathepsin-L1, Major excreted protein

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant Human Cathepsin L (114-333 aa) purified from E. coli

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1/1000-1/2000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-Cathepsin L Antikörper (ABIN317508)

Zheng, Chu, Chou, Gallati, Dier, Mirkin, Mousa, Rebbaa: "Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism." in: American journal of physiology. Cell physiology, Vol. 296, Issue 1, pp. C65-74, (2009) (PubMed).

Details zu Cathepsin L

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Andere Bezeichnung: Cathepsin L1

Hintergrund: Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L can be induced by many different signaling events, including growth factor, secondary messenger and tumor promoters. Cathepsin L is translated as pre-procathepsin L, transferred through the Golgi apparatus as procathepsin L and then stored in lysosomes as mature cathepsin L.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein

Gen-ID: 1514

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades