Cathepsin D Antikörper (AA 21-412)
Kurzübersicht für Cathepsin D Antikörper (AA 21-412) (ABIN317502)
Target
Alle Cathepsin D (CTSD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 21-412
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Spezifität
- The antibody recognizes Human Cathepsin D. Other species not tested.
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Produktmerkmale
- Synonyms: CTSD, CPSD
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Aufreinigung
- Protein-G affinity chromatography
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Immunogen
- Recombinant human Cathepsin D (21-412 aa) purified from E. coli
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Isotyp
- IgG2b
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Applikationshinweise
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ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on paraffin-embedded tissues (1: 50).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- Cathepsin D (CTSD)
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Andere Bezeichnung
- Cathepsin D
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Hintergrund
- The aspartic protease cathepsin D is one of the major proteolytic enzymes in lysosomes. The cathepsin D gene locates on chromosome 11p15.5 and spans approximately 11 kb with nine exons. Initially synthesized as an inactive precursor of pro-cathepsin D, the enzyme is subsequently converted to its active forms by proteolytic processing. Breast cancer cells, unlike normal cells, secrete high levels of pro-cathepsin D.Synonyms: CPSD, CTSD
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Gen-ID
- 1509
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UniProt
- P07339
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Pathways
- Peptide Hormone Metabolism
Target
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