SIRPA Antikörper (FITC)

Produktnummer ABIN317417

Der Maus Monoklonal Anti-SIRPA Antikörper wurde für FACS validiert. Er ist geeignet, SIRPA in Proben von Schwein zu detektieren.

Kurzübersicht für SIRPA Antikörper (FITC) (ABIN317417)

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reaktivität: Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIRPA Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: BL1H7

Produktdetails anti-SIRPA Antikörper (FITC)

Produktmerkmale: Synonyms: BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP, P84, SHPS-1, Sirp-alpha-1, Sirp-alpha-2,Sirp-alpha-3, MyD-1, SHP Substrate 1, Tyrosine-Protein Phosphatase Non-Receptor TypeSubstrate 1, Inhibitory receptor SHPS-1, Signal-Regulatory Protein Alpha-1, Brain Ig-likeMolecule with Tyrosine-based Activation Motifs, Macrophage Fusion Receptor

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Porcine alveolar macrophages

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: use 10 μL of neat - 1/10 diluted antibody to label 1x10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing. This aproduct is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu SIRPA

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Andere Bezeichnung: CD172a / SIRPA

Hintergrund: Protein tyrosine phosphatases (PTPases) SHP1 and SHP2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPa (1),SHPS1 , MyD1, BIT and p84. SIRPa is a new gene family containing at least fifteen members. SIRPa is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP2. SIRPa has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.Synonyms: BIT, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, MFR, MYD1, Macrophage fusion receptor, MyD-1 antigen, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, Signal-regulatory protein alpha-1, Sirp-alpha-2, Sirp-alpha-3, Tyrosine-protein phosphatase non-receptor type substrate 1, p84