Interferon gamma Antikörper
Kurzübersicht für Interferon gamma Antikörper (ABIN317390)
Target
Alle Interferon gamma (IFNG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody recognises Interferon gamma.
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Produktmerkmale
- Synonyms: IFN-gamma, gamma IFN
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Aufreinigung
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
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Immunogen
- Recombinant bovine IFN-gamma.
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Isotyp
- IgG1
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Applikationshinweise
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Flow Cytometry: Use 10 μL of 1/50-1/100 diluted antibody to label 10^6 cells or 100 μL wholeblood (Membrane permeabilisation is required). ELISA: 5 μg/mL as Capture antibody. This antibody may be used in combination with clone CC302 (Cat#ABIN317373) andRecombinant Bovine IFN gamma in a Sandwich ELISA or ELISPOT assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline with 0.09 % Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- Interferon gamma (IFNG)
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Andere Bezeichnung
- IFNG / Interferon gamma
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Hintergrund
- Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.Synonyms: IFN-gamma, gamma IFN
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Gen-ID
- 281237
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UniProt
- P07353
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Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie
Target
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