IL-4 Antikörper (PE)

Produktnummer ABIN317378

Der Maus Monoklonal Anti-IL-4-Antikörper wurde für FACS validiert. Er ist geeignet, IL-4 in Proben von Hund, Rind (Kuh), Schwein, Schaf, Ziege und Marder zu detektieren.

Kurzübersicht für IL-4 Antikörper (PE) (ABIN317378)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reaktivität: Hund, Rind (Kuh), Schwein, Schaf, Ziege, Marder

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: CC303

Produktdetails anti-IL-4 Antikörper (PE)

Spezifität: This antibody recognises bovine interleukin 4.

Produktmerkmale: Synonyms: IL-4, BSF1, Lymphocyte stimulatory factor 1, Binetrakin, Pitrakinra, B-cell stimulatory factor1

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 1/5.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Reconstitute with 1 mL distilled water

Konzentration: 0.1 mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide, 1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Andere Bezeichnung: Interleukin-4 / IL4

Hintergrund: IL4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.Synonyms: B-cell stimulatory factor 1, BSF1, Binetrakin, IL-4, Lymphocyte stimulatory factor 1, Pitrakinra

Gen-ID: 3565

UniProt: P05112

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation