BAFF Antikörper

Produktnummer ABIN317073

Der Maus Monoklonal anti-BAFF Antikörper (Klon 2B) (ABIN317073) detektiert spezifisch BAFF in EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BAFF Antikörper (ABIN317073)

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BAFF Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: 2B

Produktdetails anti-BAFF Antikörper

Spezifität: This antibody specifically recognises CD257 (otherwise known as BAFF/BLyS). This antibody has not been cross-adsorbed and may react with homologous proteins from related species.

Produktmerkmale: Synonyms: TNFSF13B, BLYS, TALL1, TNFSF20, ZTNF4, Tumor necrosis factor ligand superfamily member13B, TNF- and APOL-related leukocyte expressed ligand 1, B lymphocyte stimulator, Bcell-activating factor, BAFF, Dendritic cell-derived TNF-like molecule

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Recombinant full-length mature human CD257 expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 5 - 6g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Reconstitute with 0.5 mL distilled water

Konzentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.2

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution:

Haltbarkeit: 12 months

Details zu BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Andere Bezeichnung: CD257 / BAFF

Hintergrund: CD257 is a 285 amino acid type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, which acts as a B and T cell stimulator and plays a role in the development of autoimmune diseases such as systemic lupus erythematosus. CD257 is expressed by monocytes, macrophages, T cells and dendritic cells and acts through binding to CD267 (TACI), CD269 (BCMA) and CD268 (BAFFR) receptors, the latter interaction playing a critical role in the activation, survival, differentiation and proliferation of B cells.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4

Gen-ID: 10673

UniProt: Q9Y275

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response