Glypican 3 Antikörper (C-Term)
Kurzübersicht für Glypican 3 Antikörper (C-Term) (ABIN307157)
Target
Alle Glypican 3 (GPC3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Kreuzreaktivität
- Human
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Produktmerkmale
- GPC3, GPC-3, OCI5, OCI-5, GTR2-2, MXR7,Glypican-3 encodes a putative extracellular proteoglycan that is inferred to play an important role in growth control in embryonic mesodermal tissues in which it is selectively expressed. It appears to form a complex with insulin-like growth factor and hence modulate IGF2 action. Glypican-3 is the human homolog of OCI-5, a GPI-linked proteoglycan first isolated from rat intestine. Originally identified as the molecular basis for Simpson-Golabi-Behmel syndrome (SGBS) also called Simpson dysmorphia syndrome (SDYS).
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Aufreinigung
- Total IgG
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Immunogen
- C terminal recombinant protein (~70aa) which does not overlap with clone 1G12 epitope)
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Isotyp
- IgG
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Applikationshinweise
- Antibody can be used for immunohistochemistry on paraffin-embedded tissues (10 μg/mL) and Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Glypican 3 (GPC3)
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Andere Bezeichnung
- Glypican-3 (GPC3)
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UniProt
- P51654
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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