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Glypican 3 Antikörper (C-Term)

Der Schaf Polyklonal Anti-Glypican 3-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, Glypican 3 in Proben von Human zu detektieren.
Produktnummer ABIN307157

Kurzübersicht für Glypican 3 Antikörper (C-Term) (ABIN307157)

Target

Alle Glypican 3 (GPC3) Antikörper anzeigen
Glypican 3 (GPC3)

Reaktivität

  • 184
  • 64
  • 50
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 111
  • 73
  • 5
  • 2
  • 1
Schaf

Klonalität

  • 97
  • 87
  • 5
Polyklonal

Konjugat

  • 87
  • 15
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Glypican 3 Antikörper ist unkonjugiert

Applikation

  • 97
  • 86
  • 85
  • 69
  • 58
  • 30
  • 26
  • 17
  • 15
  • 15
  • 6
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 22
    • 16
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Kreuzreaktivität

    Human

    Produktmerkmale

    GPC3, GPC-3, OCI5, OCI-5, GTR2-2, MXR7,Glypican-3 encodes a putative extracellular proteoglycan that is inferred to play an important role in growth control in embryonic mesodermal tissues in which it is selectively expressed. It appears to form a complex with insulin-like growth factor and hence modulate IGF2 action. Glypican-3 is the human homolog of OCI-5, a GPI-linked proteoglycan first isolated from rat intestine. Originally identified as the molecular basis for Simpson-Golabi-Behmel syndrome (SGBS) also called Simpson dysmorphia syndrome (SDYS).

    Aufreinigung

    Total IgG

    Immunogen

    C terminal recombinant protein (~70aa) which does not overlap with clone 1G12 epitope)

    Isotyp

    IgG
  • Applikationshinweise

    Antibody can be used for immunohistochemistry on paraffin-embedded tissues (10 μg/mL) and Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Provided as solution in phosphate buffered saline with 0.08 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • Target

    Glypican 3 (GPC3)

    Andere Bezeichnung

    Glypican-3 (GPC3)

    UniProt

    P51654

    Pathways

    Glycosaminoglycan Metabolic Process
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