LASS1 Antikörper (C-Term)

Produktnummer ABIN307129

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LASS1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LASS1 Antikörper (C-Term) (ABIN307129)

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LASS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LASS1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human

Produktmerkmale: LAG1 longevity assurance homolog 1, UOG-1 protein, LAG1, LASS1,LAG1 is a longevity gene, the first such gene to be identified. Originally cloned from the yeast Saccharomyces cerevisiae. A close homolog of this gene, LAC1, has been found in the yeast genome. The human homolog of LAG1 has functions in human aging. LAG1 may be involved in neurodegenerative diseases and human aging. Lass1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. Located in the endoplasmic reticulum membrane, LAss1 is a multi-pass membrane protein.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from the C-terminal human Lass1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (1-5 μg/mL starting dilution). Other uses not yet tested. Only reacts with human Lass1 protein. Does not cross react with other species. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu LASS1

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Andere Bezeichnung: Lass1 (non-GDF1)

UniProt: P27544