LASS1 Antikörper (AA 301-350)

Produktnummer ABIN564667

Dieser Maus Polyklonal Antikörper detektiert spezifisch LASS1 in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 5+ Publikationen zitiert.

Kurzübersicht für LASS1 Antikörper (AA 301-350) (ABIN564667)

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser LASS1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-LASS1 Antikörper

Bindungsspezifität: AA 301-350

Verwendungszweck: Mouse polyclonal antibody raised against a partial recombinant LASS1.

Sequenz: YIVAFAAKVL TGQVHELKDL REYDTAEAQS LKPSKAEKPL RNGLVKDKRF

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: LASS1 (NP_067090, 301 a.a. ~ 350 a.a) partial recombinant protein with GST tag.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 50 % glycerol

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-LASS1 Antikörper (ABIN564667)

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells." in: Anticancer research, Vol. 32, Issue 3, pp. 753-60, (2012) (PubMed).

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy." in: Anticancer research, Vol. 32, Issue 7, pp. 2479-85, (2012) (PubMed).

Haddad, Khoury, Daoud, Kantar, Harati, Mousallem, Alzate, Meyer, Boustany: "CLN5 and CLN8 protein association with ceramide synthase: biochemical and proteomic approaches." in: Electrophoresis, Vol. 33, Issue 24, pp. 3798-809, (2012) (PubMed).

Senkal, Ponnusamy, Bielawski, Hannun, Ogretmen: "Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 1, pp. 296-308, (2010) (PubMed).

Senkal, Ponnusamy, Rossi, Bialewski, Sinha, Jiang, Jazwinski, Hannun, Ogretmen: "Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas." in: Molecular cancer therapeutics, Vol. 6, Issue 2, pp. 712-22, (2007) (PubMed).

Details zu LASS1

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Andere Bezeichnung: LASS1

Hintergrund: Full Gene Name: LAG1 homolog, ceramide synthase 1
Synonyms: CerS1,LAG1,MGC90349,UOG1

Gen-ID: 10715

NCBI Accession: NM_021267