CSAG2 Antikörper

Produktnummer ABIN307032

Dieser Anti-CSAG2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CSAG2 in WB und ELISA. Geeignet für Human.

Kurzübersicht für CSAG2 Antikörper (ABIN307032)

Target: CSAG2 (CSAG Family, Member 2 (CSAG2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CSAG2 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Chondrosarcoma-associated protein 2, Taxol-resistant-associated protein 3, TRAG-3, CSAG2, TRAG3,The expression of the cancer-testis antigen Taxol resistance-associated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR(10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer. First identified as a novel cancer/testis antigen, TRAG-3, (Taxol Resistance Associated Gene-3) was initially discovered in a search for new genes involved in drug resistance. Early studies of TRAG-3 revealed a minimal to absent expression in normal tissues and a marked over-expression in many carcinoma cell lines including several melanoma lines. By RT-PCR evaluation of TRAG-3 two transcripts are seen in many carcinoma cell lines with products in the the 799 bp and a second alternatively spliced transcript.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from the human Trag-3 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (0.5-2 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu CSAG2

Target: CSAG2 (CSAG Family, Member 2 (CSAG2))

Andere Bezeichnung: Trag 3 (Taxol-resistant-associated protein 3)

UniProt: Q9Y5P2