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CSAG2 Antikörper

CSAG2 Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN265187
  • Target Alle CSAG2 Antikörper anzeigen
    CSAG2 (CSAG Family, Member 2 (CSAG2))
    Reaktivität
    Human
    Wirt
    • 16
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CSAG2 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 13
    • 13
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects Trag 3. Weakly expressed in kidney. Expressed in various tumor cell lines including carcinomas, myeloid and lymphoid malignancies, melanomas and prostate cancer. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40).
    Aufreinigung
    Purified
    Immunogen
    Synthetic peptide derived from the human Trag-3 protein
    Isotyp
    IgG
    Top Product
    Discover our top product CSAG2 Primärantikörper
  • Applikationshinweise
    Western blot: 0.5-2 μg/mLELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate buffered saline with 0.08 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
  • Target
    CSAG2 (CSAG Family, Member 2 (CSAG2))
    Andere Bezeichnung
    CSAG2 (CSAG2 Produkte)
    Synonyme
    CSAG1 antikoerper, CSAG3B antikoerper, CSAG3 antikoerper, CT24.2 antikoerper, TRAG-3 antikoerper, TRAG3 antikoerper, chondrosarcoma-associated gene 2/3 protein antikoerper, CSAG family member 2 antikoerper, LOC705860 antikoerper, LOC738247 antikoerper, CSAG2 antikoerper
    Hintergrund
    The expression of the cancer-testis antigen Taxol resistance-associated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR(10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer. First identified as a novel cancer/testis antigen, TRAG-3, (Taxol Resistance Associated Gene-3) was initially discovered in a search for new genes involved in drug resistance. Early studies of TRAG-3 revealed a minimal to absent expression in normal tissues and a marked over-expression in many carcinoma cell lines including several melanoma lines. By RT-PCR evaluation of TRAG-3 two transcripts are seen in many carcinoma cell lines with products in the the 799 bp and a second alternatively spliced transcript.Synonyms: CT24.2, Cancer/testis antigen 24.2, Chondrosarcoma-associated gene 2/3 protein, TRAG-3, TRAG3, Taxol-resistant-associated gene 3 protein
    Gen-ID
    389903
    NCBI Accession
    NP_001074317
    UniProt
    Q9Y5P2
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