RGR Antikörper (Intracellular)

Produktnummer ABIN306933

Dieses Anti-RGR-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von RGR in IHC und WB. Geeignet für Ratte.

Kurzübersicht für RGR Antikörper (Intracellular) (ABIN306933)

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RGR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Klon: 5G10

Produktdetails anti-RGR Antikörper

Bindungsspezifität: Intracellular

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.

Aufreinigung: Protein A/G Chromatography

Immunogen: Mouse monoclonal antibody raised to a synthetic peptide corresponding to the third intracellular loop of the rat alpha 2b adrenergic receptor.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Antibody detects alpha2B Adrenergic Receptors in Western blots (1-5 μg/mL) and immunohistochemistry. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu RGR

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Andere Bezeichnung: Adrenergic Receptor

UniProt: P19328