RGR Antikörper

Produktnummer ABIN7248914

Produktdetails anti-RGR Antikörper

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human RGR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.78 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RGR

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Andere Bezeichnung: RGR (RGR Produkte)

Synonyme: RP44 antikoerper, MGC84794 antikoerper, RGR antikoerper, rgr antikoerper, zgc:110660 antikoerper, rgr2 antikoerper, wu:fb64c10 antikoerper, zgc:109930 antikoerper, retinal G protein coupled receptor antikoerper, retinal G protein coupled receptor L homeolog antikoerper, retinal G protein coupled receptor a antikoerper, retinal G protein coupled receptor b antikoerper, RGR antikoerper, Rgr antikoerper, rgr.L antikoerper, rgr antikoerper, rgra antikoerper, rgrb antikoerper

Hintergrund: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 32 kDa

UniProt: P47804