GPR68 Antikörper

Produktnummer ABIN306927

Dieses Anti-GPR68-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GPR68 in WB, IHC und InhA. Geeignet für Human.

Kurzübersicht für GPR68 Antikörper (ABIN306927)

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR68 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Inhibition Assay (InhA)

Produktdetails anti-GPR68 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: GPR68, Ovarian Cancer G Protein-Coupled Receptor 1,OGR1 (originally identified as GPR68) is a high-affinity receptor for sphingosylphosphorylcholine (SPC). SPC is a member of a class of bioactive lipids which regulate cellular functions. These functions include cell proliferation and growth inhibition, smooth muscle contration and wound healing. SPC also stimulated signalling pathways that induce tyrosine phosphorylation, activate MAP kinases and protein kinase C, modify ion channel activity and increase intracellular Ca2+ concentration. OGR1 is expressed in placenta, lung, liver, spleen, testis, small intestine and peripheral blood leukocytes. It is not found in thymus, ovary, colon, skeletal muscle, kidney or pancreas.

Aufreinigung: Protein A/G Chromatography

Immunogen: Rabbits were immunized with recombinant protein derived from human OGR1 (GPR68).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (5-10 μg/mL). Western blot should be visualized using a high sensitivity secondary/substrate system (i.e. Pierce's SuperSignal West Femto Maximum Sensitivity Substrate). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Andere Bezeichnung: OGR1/GPR68

UniProt: Q15743