LPAR3 Antikörper (C-Term)

Produktnummer ABIN306802

Produktdetails anti-LPAR3 Antikörper

Target: LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LPAR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Produktmerkmale: Endothelial cell differentiation gene 7 C-terminal, Lysophosphatidic Acid Receptor-4 (LPA3),Endothelial Cell Differentiation Gene-7 (EDG-7) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-7 is lysophospholipid. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-7 is expressed in prostate as well as other tissues.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Antibody raised against a unique synthetic peptide derived from the C-terminal of the human EDG7 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Detects recombinant EDG-7 receptors by Western blot. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu LPAR3

Target: LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))

Andere Bezeichnung: Lysophosphatidic Acid Receptor 3 CT (EDG-7) (LPAR3 Produkte)

Synonyme: EDG7 antikoerper, Edg-7 antikoerper, GPCR antikoerper, HOFNH30 antikoerper, LP-A3 antikoerper, LPA3 antikoerper, RP4-678I3 antikoerper, Edg7 antikoerper, lpA3 antikoerper, lysophosphatidic acid receptor 3 antikoerper, LPAR3 antikoerper, LOC100038016 antikoerper, Lpar3 antikoerper

UniProt: Q9UBY5

Pathways: Regulation of Cell Size