EPH Receptor B1 Antikörper (C-Term)

Produktnummer ABIN306670

Dieser Schaf Polyklonal Antikörper detektiert spezifisch EPH Receptor B1 in IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für EPH Receptor B1 Antikörper (C-Term) (ABIN306670)

Target: EPH Receptor B1 (EPHB1)

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-EPH Receptor B1 Antikörper

Bindungsspezifität: AA 883-984, C-Term

Verwendungszweck: Sheep anti Human ELK rec tyr Kinase (Eph B1 SAM.)

Kreuzreaktivität: Ratte

Produktmerkmale: The immunogen used for the anti-human ephB1 (Elk receptor) -SAM region was a GST fusion protein ephB1 (Elk receptor) -SAM corresponding to amino acid sequence 883-984 of the C terminus region and having a molecular weight of 116 kD. ephB1, previously known as Elk (eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: A GST fusion protein ephB1 (Elk receptor) -SAM corresponding to amino acid sequence 883-984 of the C terminus region and having a molecular weight of 116 kD

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Applications: 1-10 μg/mL for Western Blotting and 10-20 μg/mL for Immunoprecipitation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu EPH Receptor B1

Target: EPH Receptor B1 (EPHB1)

Andere Bezeichnung: ELK rec tyr Kinase (Eph B1 SAM)

Hintergrund: Eph B1 (ELK receptor) SAM, Tyrosine-protein kinase receptor EPH-2, Ephrin type B receptor 1, HEK6

UniProt: P54762

Pathways: RTK Signalweg