EPH Receptor B1 Antikörper (AA 620-1596)

Produktnummer ABIN306670

Dieses Schaf Polyklonal-Antikörper erkennt spezifisch EPH Receptor B1 in WB, IHC und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für EPH Receptor B1 Antikörper (AA 620-1596) (ABIN306670)

Target: EPH Receptor B1 (EPHB1)

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-EPH Receptor B1 Antikörper

Bindungsspezifität: AA 620-1596

Kreuzreaktivität: Ratte

Produktmerkmale: Eph B1 (ELK receptor) SAM, Tyrosine-protein kinase receptor EPH-2, Ephrin type B receptor 1, HEK6,Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicated during the process of spermiogenesis and in the actin-based stellate morphology of mesangial cells

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Sheep were immunized with a recombinant protein corresponding to amino acids 620-1596 of the SSeCKS protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blot (2-5 μg/mL), immunohistochemistry and immunoprecipitation. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu EPH Receptor B1

Target: EPH Receptor B1 (EPHB1)

Andere Bezeichnung: ELK rec tyr Kinase (Eph B1 SAM)

Pathways: RTK Signalweg