PPP2R5A Antikörper

Produktnummer ABIN306652

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PPP2R5A in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PPP2R5A Antikörper (ABIN306652)

Target: PPP2R5A (Protein Phosphatase 2, Regulatory Subunit B' alpha (PPP2R5A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PPP2R5A Antikörper

Verwendungszweck: Rabbit anti Human Protein Phosphatase 2 A/B beta

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Produktmerkmale: A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein phosphorylation is one of the most common forms of reversible protein posttranslational modification (PTM), with up to 30 % of all proteins being phosphorylated at any given time. Protein kinases (PKs) are the effectors of phosphorylation and catalyse the transfer of a γ-phosphate from ATP to specific amino acids on proteins. Several hundred PKs exist in mammals and are classified into distinct super-families. Proteins are phosphorylated predominantly on Ser, Thr and Tyr residues, which account for 79.3, 16.9 and 3.8 % respectively of the phosphoproteome, at least in mammals. In contrast, protein phosphatases (PPs) are the primary effectors of dephosphorylation and can be grouped into three main classes based on sequence, structure and catalytic function. The largest class of PPs is the phosphoprotein phosphatase (PPP) family comprising PP1, PP2A, PP2B, PP4, PP5, PP6 and PP7, and the protein phosphatase Mg²+- or Mn²+-dependent (PPM) family, composed primarily of PP2C.

Aufreinigung: Ammonium Sulfate Precipitation

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Applications: Immunoblotting 1:500 to 1:1,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu PPP2R5A

Target: PPP2R5A (Protein Phosphatase 2, Regulatory Subunit B' alpha (PPP2R5A))

Andere Bezeichnung: Protein Phosphatase 2 A/B beta

Hintergrund: Pp2A/Bb, rabbit anti protein phosphatase 2A, B subunit beta, PP2A B subunit beta

UniProt: Q15172, Q6PD03, P36877

Pathways: PI3K-Akt Signalweg