Retinoblastoma Protein (Rb) Antikörper (AA 387-928)

Produktnummer ABIN306637

Dieser Maus Monoklonal Antikörper detektiert spezifisch Retinoblastoma Protein (Rb) in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Huhn und Nerz.

Kurzübersicht für Retinoblastoma Protein (Rb) Antikörper (AA 387-928) (ABIN306637)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reaktivität: Human, Maus, Ratte, Huhn, Nerz

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: XZ91

Produktdetails anti-Retinoblastoma Protein (Rb) Antikörper

Bindungsspezifität: AA 387-928

Verwendungszweck: Mouse anti Human Rb (Retinoblastoma)

Produktmerkmale: The immunogen for the anti-human retinoblastoma (Rb) was a recombinant protein corresponding to amino acids 393 to 572 of the human retinoblastoma sequence. Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.

Aufreinigung: Protein A/G Chromatography

Immunogen: A recombinant protein corresponding to amino acids 387 to 928 of the human retinoblastoma sequence

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Applications: Western Blot, Immunofluorescence

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu Retinoblastoma Protein (Rb)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Andere Bezeichnung: Rb (Retinoblastoma)

Hintergrund: Retinoblastoma-associated protein, pRb, pp110, p105-Rb

UniProt: P06400

Pathways: Mitotic G1-G1/S Phases