LMO2 Antikörper (full length)
Kurzübersicht für LMO2 Antikörper (full length) (ABIN306631)
Target
Alle LMO2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- full length
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Verwendungszweck
- Sheep anti Human Rhombotin 2
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Produktmerkmale
- Two homologues of the rhombotin gene have now been isolated. One of these, designated Rhom-2, is located on human chromosome 11 at band 11p13, where a cluster of T-cell leukemia-specific translocations occur, all translocation breakpoints at 11p13 are upstream of the Rhom-2 gene. Human and mouse Rhom-2 are highly conserved and, like rhombotin, encode two tandem cysteine-rich LIM domains. Rhom-2 mRNA is expressed in early mouse development in central nervous system, lung, kidney, liver, and spleen but only very low levels occur in thymus. The Rhom-2 gene is such a common site of chromosomal damage in T-cell tumors. Chromosome bands 11p15 (rhombotin) and 11p13 (Rhom-2) are consistent sites of chromosome translocation in T-cell leukemia, with the 11p15 target more rarely involved.
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Aufreinigung
- Ammonium Sulfate Precipitation
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Immunogen
- Full length rhombotin 2 protein
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Isotyp
- IgG
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Applikationshinweise
- Western Blots at 1-10 μg /mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
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Andere Bezeichnung
- Rhombotin 2
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Hintergrund
- LIM domain only protein, cysteine-rich protein TTG-2, T-cell translocation protein 2
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UniProt
- P25791
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Pathways
- Chromatin Binding
Target
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