p130 Antikörper
Kurzübersicht für p130 Antikörper (ABIN306630)
Target
Alle p130 (RBL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Mouse anti Human p130
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Produktmerkmale
- P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130 kDa.
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Aufreinigung
- Protein A/G Chromatography
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Isotyp
- IgG1
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Applikationshinweise
- Western Blots at 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
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Andere Bezeichnung
- p130
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Hintergrund
- P130, Retinoblastoma-like protein 2, RBR-2, PRB2
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Molekulargewicht
- 130kDa
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UniProt
- Q08999, Q64700, O55081
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
Target
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