p107 Antikörper

Produktnummer ABIN306628

Dieses Maus Monoklonal-Antikörper erkennt spezifisch p107 in . Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für p107 Antikörper (ABIN306628)

Target: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser p107 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Klon: KAB6

Produktdetails anti-p107 Antikörper

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Details zu p107

Target: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Andere Bezeichnung: p107

Hintergrund: The immunogen used was a GST fusion protein to the N terminus of p107. p107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors. KAB6 recognizes both the phosphorylated and unphosphorylated forms of p107 at a MW of 107kDa. Synonyms: p107, Retinoblastoma-like protein 1, PRB1, 107 kda retinoblastoma-associated protein.

UniProt: P28749

Pathways: Zellzyklus, Mitotic G1-G1/S Phases