ErbB2/Her2 Antikörper (full length)
Kurzübersicht für ErbB2/Her2 Antikörper (full length) (ABIN306627)
Target
Alle ErbB2/Her2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- full length
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Verwendungszweck
- Sheep anti Human HER2/neu
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Produktmerkmale
- c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25 % of primary breast and ovarian tumors were found to overexpress the protein.
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Aufreinigung
- Ammonium Sulfate Precipitation
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Immunogen
- Full-length recombinant c-erbB-2/HER2/neu protein.
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Isotyp
- IgG
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Applikationshinweise
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/ml
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Andere Bezeichnung
- c-ErbB-2
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Hintergrund
- P185erbB2, MLN 19, CD340, c-ErbB-2
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UniProt
- P04626
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
Target
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