ErbB2/Her2 Antikörper
Kurzübersicht für ErbB2/Her2 Antikörper (ABIN306627)
Target
Alle ErbB2/Her2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Isotyp
- IgG
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Applikationshinweise
- Antibody can be used for Western blotting (5-10 ug/ml). Positive Control: Breast carcinomas.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/ml
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Lagerung
- -20 °C
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Andere Bezeichnung
- c-ErbB-2
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Hintergrund
- C-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. Synonyms: HER2, neu, p185erbB2, MLN 19, CD340.
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UniProt
- P04626
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
Target
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