CD73 Antikörper (AA 27-252)
Kurzübersicht für CD73 Antikörper (AA 27-252) (ABIN306435)
Target
Alle CD73 (NT5E) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 27-252
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Verwendungszweck
- Human 5'-Nucleotidase/CD73 antibody
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Aufreinigung
- Purified
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Immunogen
- Recombinant human CD73 (27-252aa) purified from E. coli
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Isotyp
- IgG2b kappa
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Applikationshinweise
- Recommended dilution 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing cycles
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
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Andere Bezeichnung
- 5'-Nucleotidase/CD73
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Hintergrund
- CD73 (Ecto-5-nucleotidase, 5-NT) is a membrane-bound glycoprotein that functions to hydrolyze extracellular nucleoside monophosphates into bioactive nucleoside intermediates. This enables the uptake of adenosine, inosine, and guanosine into the cell and their subsequent reconversion into ATP and GTP in the purine salvage pathway. The expression of CD73 on neuronal cells has been described during developmental processes and, on lymphocytes, CD73 serves as a maturation marker, being absent from the surface of both immature B and T cells.
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NCBI Accession
- NP_002517
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Pathways
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
Target
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