CD86 Antikörper
Kurzübersicht für CD86 Antikörper (ABIN305514)
Target
Alle CD86 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The antibody reacts with CD86, a 70 kD type I transmembrane gycoprotein of the immunoglobulin supergene family, expressed on antigen-presenting cells such as dendritic cells, macrophages or activated B lymphocytes.
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Aufreinigung
- Protein A purified
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Immunogen
- B-lymphoblastoid cell line ARH 77.
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Isotyp
- IgG1
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Applikationshinweise
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Approved: Block, Flo, Func, IHC, IHC-Fr, IP, Neut, WB
Usage: Flow Cytometry: Recommended dilution - 5 μg/mL. Functional Application: The antibody BU63 blocks mixed lymphocyte reaction (MLR) and binding of soluble CTLA-4 (CD152)-mulg fusion protein to CD86 (B7-2).
Not recommended for: IHC-P -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, approx, pH 7.4.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- CD86
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Andere Bezeichnung
- CD86
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Hintergrund
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Name/Gene ID: CD86
Synonyms: CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 Molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2 -
Gen-ID
- 942
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UniProt
- P42081
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Target
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