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VRK1 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VRK1 in WB. Er zeigt eine Reaktivität gegenüber Human und Ratte.
Produktnummer ABIN3044560

Kurzübersicht für VRK1 Antikörper (C-Term) (ABIN3044560)

Target

Alle VRK1 Antikörper anzeigen
VRK1 (Vaccinia Related Kinase 1 (VRK1))

Reaktivität

  • 50
  • 11
  • 3
Human, Ratte

Wirt

  • 42
  • 8
Kaninchen

Klonalität

  • 44
  • 6
Polyklonal

Konjugat

  • 25
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser VRK1 Antikörper ist unkonjugiert

Applikation

  • 42
  • 15
  • 13
  • 13
  • 10
  • 10
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 292-329, C-Term

    Verwendungszweck

    Anti-VRK1 Antibody Picoband®

    Sequenz

    EKNKPGEIAK YMETVKLLDY TEKPLYENLR DILLQGLK

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-VRK1 Antibody Picoband® (ABIN3044560). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human VRK1, different from the related mouse sequence by three amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Rat
    1. "Entrez Gene: VRK1 vaccinia related kinase 1". 2. Nezu J, Oku A, Jones MH, Shimane M (Feb 1998). "Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to vaccinia virus B1R kinase". Genomics 45 (2): 327-31.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    VRK1 (Vaccinia Related Kinase 1 (VRK1))

    Andere Bezeichnung

    VRK1

    Hintergrund

    Synonyms: Serine/threonine-protein kinase VRK1,2.7.11.1,Vaccinia-related kinase 1,VRK1,

    Tissue Specificity: Widely expressed. Highly expressed in fetal liver, testis and thymus. .

    Background: Serine/threonine-protein kinase VRK1 is an enzyme that in humans is encoded by the VRK1 gene. This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

    Molekulargewicht

    55 kDa

    Gen-ID

    7443

    UniProt

    Q99986
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