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VRK1 Antikörper (C-Term)

VRK1 Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044560
  • Target Alle VRK1 Antikörper anzeigen
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    Bindungsspezifität
    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 292-329, C-Term
    Reaktivität
    • 48
    • 11
    • 3
    Human, Ratte
    Wirt
    • 41
    • 7
    Kaninchen
    Klonalität
    • 43
    • 5
    Polyklonal
    Konjugat
    • 24
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VRK1 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 15
    • 12
    • 12
    • 9
    • 9
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Anti-VRK1 Antibody Picoband®
    Sequenz
    EKNKPGEIAK YMETVKLLDY TEKPLYENLR DILLQGLK
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-VRK1 Antibody Picoband® (ABIN3044560). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human VRK1, different from the related mouse sequence by three amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product VRK1 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Human, Rat
    1. "Entrez Gene: VRK1 vaccinia related kinase 1". 2. Nezu J, Oku A, Jones MH, Shimane M (Feb 1998). "Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to vaccinia virus B1R kinase". Genomics 45 (2): 327-31.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    Andere Bezeichnung
    VRK1 (VRK1 Produkte)
    Hintergrund

    Synonyms: Serine/threonine-protein kinase VRK1,2.7.11.1,Vaccinia-related kinase 1,VRK1,

    Tissue Specificity: Widely expressed. Highly expressed in fetal liver, testis and thymus. .

    Background: Serine/threonine-protein kinase VRK1 is an enzyme that in humans is encoded by the VRK1 gene. This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

    Molekulargewicht
    55 kDa
    Gen-ID
    7443
    UniProt
    Q99986
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