SIX Homeobox 1 Antikörper (C-Term)

Produktnummer ABIN3044544

Dieses Anti-SIX Homeobox 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SIX Homeobox 1 in WB. Geeignet für Human.

Kurzübersicht für SIX Homeobox 1 Antikörper (C-Term) (ABIN3044544)

Target: SIX Homeobox 1 (SIX1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIX Homeobox 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SIX Homeobox 1 Antikörper

Bindungsspezifität: AA 245-282, C-Term

Verwendungszweck: Anti-SIX1 Antibody Picoband®

Sequenz: NYSLPGLTAS QPSHGLQTHQ HQLQDSLLGP LTSSLVDL

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SIX1 Antibody Picoband® (ABIN3044544). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SIX1, different from the related mouse sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: SIX1 sine oculis homeobox homolog 1 (Drosophila)". 2. Boucher CA, Carey N, Edwards YH, Siciliano MJ, Johnson KJ (Apr 1996). "Cloning of the human SIX1 gene and its assignment to chromosome 14". Genomics 33 (1): 140-2. 3. Ruf RG, Xu PX, Silvius D, Otto EA, Beekmann F, Muerb UT, Kumar S, Neuhaus TJ, Kemper MJ, Raymond RM, Brophy PD, Berkman J, Gattas M, Hyland V, Ruf EM, Schwartz C, Chang EH, Smith RJ, Stratakis CA, Weil D, Petit C, Hildebrandt F (May 2004). "SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes". Proceedings of the National Academy of Sciences of the United States of America 101 (21): 8090-5.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu SIX Homeobox 1

Target: SIX Homeobox 1 (SIX1)

Andere Bezeichnung: SIX1

Hintergrund:

Synonyms: Homeobox protein SIX1,Sine oculis homeobox homolog 1,SIX1,

Tissue Specificity: Specifically expressed in skeletal muscle.

Background: Homeobox protein SIX1 (Sineoculis homeobox homolog 1) is a protein that in humans is encoded by the SIX1 gene. It is mapped to 14q23.1. The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).

Molekulargewicht: 37 kDa

Gen-ID: 6495

UniProt: Q15475

Pathways: Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development