PAK3 Antikörper (N-Term)

Produktnummer ABIN3044532

Produktdetails anti-PAK3 Antikörper

Target: PAK3

Bindungsspezifität: AA 13-49, N-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase PAK 3(PAK3) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: APPLRMNSNN RDSSALNHSS KPLPMAPEEK NKKARLR

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase PAK 3(PAK3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: p21 protein (Cdc42/Rac)-activated kinase 3
Protein Name: Serine/threonine-protein kinase PAK 3

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PAK3 (13-49aa APPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLR), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu PAK3

Target: PAK3

Andere Bezeichnung: PAK3 (PAK3 Produkte)

Synonyme: CDKN1A antikoerper, MRX30 antikoerper, MRX47 antikoerper, OPHN3 antikoerper, PAK3beta antikoerper, bPAK antikoerper, hPAK3 antikoerper, PAK-3 antikoerper, Pak65alpha antikoerper, Pak65beta antikoerper, Stk4 antikoerper, beta-PAK antikoerper, XPak3 antikoerper, bpak antikoerper, cdkn1a antikoerper, mrx30 antikoerper, mrx47 antikoerper, ophn3 antikoerper, pak3 antikoerper, pak3-A antikoerper, pak3beta antikoerper, p21 (RAC1) activated kinase 3 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 3 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog antikoerper, PAK3 antikoerper, Pak3 antikoerper, pak3.L antikoerper

Hintergrund: Serine/threonine-protein kinase PAK 3 is an enzyme that in humans is encoded by the PAK3 gene. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms: Beta PAK antibody|bPAK antibody|CDKN1A antibody|hPAK3 antibody|Mental retardation X linked 30 antibody|MRX30 antibody|MRX47 antibody| Oligophrenin 3 antibody|OPHN3 antibody|p21 (CDKN1A) activated kinase 3 antibody|p21 activated kinase 3 antibody|p21 CDKN1A activated kinase 3 antibody|P21 protein (Cdc42/Rac) activated kinase 3 antibody|PAK-3 antibody|PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 antibody|PAK3beta antibody|Pak65alpha antibody|Pak65beta antibody|Serine threonine protein kinase PAK 3 antibody|Stk4 antibody

Gen-ID: 5063

UniProt: O75914