Coxsackie Adenovirus Receptor Antikörper (C-Term)

Produktnummer ABIN3044083

Produktdetails anti-Coxsackie Adenovirus Receptor Antikörper

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Bindungsspezifität: AA 313-328, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coxsackie Adenovirus Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Coxsackievirus and adenovirus receptor(CXADR) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: YSKTQYNQVP SEDFER

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Coxsackievirus and adenovirus receptor(CXADR) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: coxsackie virus and adenovirus receptor
Protein Name: Coxsackievirus and adenovirus receptor(CAR/hCAR)

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Coxsackie Adenovirus Receptor(313-328aa YSKTQYNQVPSEDFER), identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Coxsackie Adenovirus Receptor

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Andere Bezeichnung: CXADR (CXADR Produkte)

Synonyme: CAR antikoerper, CAR4/6 antikoerper, HCAR antikoerper, Car1 antikoerper, car antikoerper, cb331 antikoerper, fb76g12 antikoerper, wu:fb76g12 antikoerper, 2610206D03Rik antikoerper, AU016810 antikoerper, AW553441 antikoerper, MCAR antikoerper, MCVADR antikoerper, hcar antikoerper, xCAR antikoerper, CXADR antikoerper, CXADR, Ig-like cell adhesion molecule antikoerper, coxsackie virus and adenovirus receptor antikoerper, CXADR, Ig-like cell adhesion molecule L homeolog antikoerper, CXADR antikoerper, Cxadr antikoerper, cxadr antikoerper, cxadr.L antikoerper

Hintergrund: CXADR(Coxsackie virus and adenovirus receptor) is a protein that in humans is encoded by the CXADR gene, also known as CAR,CVB3-binding protein, Coxsackievirus B-adenovirus receptor. The CAR cDNA encodes a predicted 365-amino acid polypeptide that contains a single transmembrane domain and is a member of the immunoglobulin superfamily. By Northern blot analysis, they detected highest expression of 1.4-kb and 6-kb CXADR transcripts in pancreas, brain, heart, small intestine, testis, and prostate, lower expression in liver and lung, and no expression in kidney, placenta, peripheral blood leukocytes, thymus, and spleen. In comparison, mouse Cxadr showed highest expression in liver, and lower levels in kidney, heart, lung, and brain. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins , such as: fibronectin, agrin, laminin-1 and tenascin-R.

Synonyms: 46 kD coxsackievirus and adenovirus receptor CAR protein antibody|46 kD coxsackievirus and adenovirus receptor protein antibody|CAR antibody|CAR4/6 antibody|Coxsackie virus and adenovirus receptor antibody|Coxsackie virus B receptor antibody|Coxsackievirus and adenovirus receptor antibody|Coxsackievirus B adenovirus receptor antibody|Coxsackievirus B-adenovirus receptor antibody|CVB3 binding protein antibody|CVB3-binding protein antibody|Cxadr antibody|CXAR_HUMAN antibody|hCAR antibody|HCVADR antibody

UniProt: P78310

Pathways: Cell-Cell Junction Organization