Coxsackie Adenovirus Receptor Antikörper (N-Term)

Produktnummer ABIN6256932

Produktdetails anti-Coxsackie Adenovirus Receptor Antikörper

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coxsackie Adenovirus Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: CXADR Antibody detects endogenous levels of total CXADR.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CXADR, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Coxsackie Adenovirus Receptor

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Andere Bezeichnung: CXADR (CXADR Produkte)

Synonyme: CAR antikoerper, CAR4/6 antikoerper, HCAR antikoerper, Car1 antikoerper, car antikoerper, cb331 antikoerper, fb76g12 antikoerper, wu:fb76g12 antikoerper, 2610206D03Rik antikoerper, AU016810 antikoerper, AW553441 antikoerper, MCAR antikoerper, MCVADR antikoerper, hcar antikoerper, xCAR antikoerper, CXADR antikoerper, CXADR, Ig-like cell adhesion molecule antikoerper, coxsackie virus and adenovirus receptor antikoerper, CXADR, Ig-like cell adhesion molecule L homeolog antikoerper, CXADR antikoerper, Cxadr antikoerper, cxadr antikoerper, cxadr.L antikoerper

Hintergrund:

Description: Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

Gene: CXADR

Molekulargewicht: 40 kDa

Gen-ID: 1525

UniProt: P78310

Pathways: Cell-Cell Junction Organization