PGK1 Antikörper (Middle Region)
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- Target Alle PGK1 Antikörper anzeigen
- PGK1 (Phosphoglycerate Kinase 1 (PGK1))
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Bindungsspezifität
- AA 166-180, Middle Region
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PGK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunocytochemistry (ICC)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Phosphoglycerate kinase 1(PGK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequenz
- FGTAHRAHSS MVGVN
- Kreuzreaktivität (Details)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Produktmerkmale
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Rabbit IgG polyclonal antibody for Phosphoglycerate kinase 1(PGK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: phosphoglycerate kinase 1
Protein Name: Phosphoglycerate kinase 1 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human PGK1(166-180aa FGTAHRAHSSMVGVN), identical to the related rat and mouse sequences.
- Isotyp
- IgG
- Top Product
- Discover our top product PGK1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for PGK1 is approximately 1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Rat, Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB and ICC.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Haltbarkeit
- 12 months
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- Target
- PGK1 (Phosphoglycerate Kinase 1 (PGK1))
- Andere Bezeichnung
- PGK1 (PGK1 Produkte)
- Synonyme
- MIG10 antikoerper, PGKA antikoerper, Pgk-1 antikoerper, Pgk antikoerper, PGK antikoerper, wu:fd59b07 antikoerper, wu:fj36g06 antikoerper, zgc:56252 antikoerper, zgc:77899 antikoerper, PGK1 antikoerper, phosphoglycerate kinase 1 antikoerper, pgk2 antikoerper, pgka antikoerper, phosphoglycerate kinase 1 antikoerper, phosphoglycerate kinase 1 L homeolog antikoerper, PGK1 antikoerper, Pgk1 antikoerper, pgk1 antikoerper, LOC100348124 antikoerper, pgk1.L antikoerper
- Hintergrund
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PGK1 (Phosphoglycerate Kinase 1), also known as PGKA, is an enzyme that in humans is encoded by the PGK1 gene. The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. And the encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.
Synonyms: Cell migration-inducing gene 10 protein antibody|MGC117307 antibody|MGC8947 antibody|MIG10 antibody|pgk1 antibody|PGK1_HUMAN antibody|PGKA antibody|Phosphoglycerate kinase 1 antibody|Primer recognition protein 2 antibody|PRP 2 antibody - UniProt
- P00558
- Pathways
- Cellular Glucan Metabolic Process
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