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BMP5 Antikörper (C-Term)

Dieses Anti-BMP5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BMP5 in WB, IHC, ELISA und FACS. Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN3043800

Kurzübersicht für BMP5 Antikörper (C-Term) (ABIN3043800)

Target

Alle BMP5 Antikörper anzeigen
BMP5 (Bone Morphogenetic Protein 5 (BMP5))

Reaktivität

  • 67
  • 26
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 68
  • 11
  • 1
Kaninchen

Klonalität

  • 70
  • 10
Polyklonal

Konjugat

  • 39
  • 11
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BMP5 Antikörper ist unkonjugiert

Applikation

  • 61
  • 32
  • 24
  • 16
  • 13
  • 13
  • 11
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 11
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 332-365, C-Term

    Verwendungszweck

    Anti-BMP5 Antibody Picoband®

    Sequenz

    HQDSSRMSSV GDYNTSEQKQ ACKKHELYVS FRDL

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-BMP5 Antibody Picoband® (ABIN3043800). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human BMP-5, different from the related mouse sequence by three amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: BMP5 bone morphogenetic protein 5". 2. Beck HN, Drahushuk K, Jacoby DB, Higgins D, Lein PJ (Mar 2003). "Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons". BMC Neurosci 2: 12. 3. Hahn GV, Cohen RB, Wozney JM, Levitz CL, Shore EM, Zasloff MA, Kaplan FS (Dec 1992). "A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7". Genomics 14 (3): 759-62.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Wang, Xue, Zhao, Liu, Ma, Ma: "Form-deprivation myopia induces decreased expression of bone morphogenetic protein-2, 5 in guinea pig sclera." in: International journal of ophthalmology, Vol. 8, Issue 1, pp. 39-45, (2015) (PubMed).

  • Target

    BMP5 (Bone Morphogenetic Protein 5 (BMP5))

    Andere Bezeichnung

    BMP5

    Hintergrund

    Synonyms: Bone morphogenetic protein 5,BMP-5,BMP5,

    Tissue Specificity: Expressed in the lung and liver.

    Background: Bone morphogenetic protein 5?is a?protein?that in humans is encoded by the?BMP5?gene. This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. And this protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.

    Molekulargewicht

    51 kDa

    Gen-ID

    653

    UniProt

    P22003

    Pathways

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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