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Angiopoietin 1 Antikörper (AA 16-350)

This anti-Angiopoietin 1 antibody (ABIN3043724) is a Rabbit Polyclonal antibody detecting Angiopoietin 1 in WB. Suitable for Human.
Produktnummer ABIN3043724

Kurzübersicht für Angiopoietin 1 Antikörper (AA 16-350) (ABIN3043724)

Target

Alle Angiopoietin 1 (ANGPT1) Antikörper anzeigen
Angiopoietin 1 (ANGPT1)

Reaktivität

  • 110
  • 35
  • 34
  • 13
  • 6
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 119
  • 19
  • 1
  • 1
Kaninchen

Klonalität

  • 102
  • 38
Polyklonal

Konjugat

  • 77
  • 19
  • 10
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Angiopoietin 1 Antikörper ist unkonjugiert

Applikation

  • 105
  • 56
  • 33
  • 33
  • 26
  • 15
  • 13
  • 13
  • 8
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 11
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 16-350

    Verwendungszweck

    Anti-Angiopoietin 1/ANGPT1 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Angiopoietin 1/ANGPT1 Antibody Picoband® (ABIN3043724). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Angiopoietin 1 recombinant protein (Position: H16-N350). Human Angiopoietin 1 shares 96% amino acid (aa) sequence with both mouse and rat Angiopoietin 1.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human
    1. "Entrez Gene: ANGPT1 angiopoietin 1". Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. 2. Suri, C., Jones, P. F., Patan, S., Bartunkova, S., Maisonpierre, P. C., Davis, S., Sato, T. N., Yancopoulos, G. D. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87: 1171-1180, 1996. 3. Cheung, A. H., Stewart, R. J., Marsden, P. A. Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23. Genomics 48: 389-391, 1998.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Sun, Wang, Cheng, Wang, Li, Xue, Wang, Ai, Zhang, Xu, Wang, Ji: "Morroniside improves microvascular functional integrity of the neurovascular unit after cerebral ischemia." in: PLoS ONE, Vol. 9, Issue 6, pp. e101194, (2014) (PubMed).

  • Target

    Angiopoietin 1 (ANGPT1)

    Andere Bezeichnung

    ANGPT1

    Hintergrund

    Synonyms: Angiopoietin-1,ANG-1,ANGPT1,KIAA0003,

    Tissue Specificity: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis. .

    Background: Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin 1 is mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.

    Sequence Similarities: Contains 1 fibrinogen C-terminal domain.

    Molekulargewicht

    65 kDa

    Gen-ID

    284

    UniProt

    Q15389

    Pathways

    RTK Signalweg, Glycosaminoglycan Metabolic Process
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