Cytochrome C Antikörper (C-Term)
Kurzübersicht für Cytochrome C Antikörper (C-Term) (ABIN3043697)
Target
Alle Cytochrome C (CYCS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 91-105, C-Term
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                                            Verwendungszweck
- Anti-Cytochrome C/CYCS Antibody Picoband®
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                                            Sequenz
- ERADLIAYLK KATNE
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                                            Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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                                            Produktmerkmale
- Anti-Cytochrome C/CYCS Antibody (ABIN3043697). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            Aufreinigung
- Immunogen affinity purified.
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                                            Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human Cytochrome C, identical to the related mouse and rat sequences.
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
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                        Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat 
 Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
 Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, Rat, Mouse
 Immunocytochemistry , 0.5-1 μg/mL, Human, -
 Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
 Flow Cytometry (Fixed), 1-μg/1x106 cells, Human
 1. Li, K., Li, Y., Shelton, J. M., Richardson, J. A., Spencer, E., Chen, Z. J., Wang, X., Williams, R. S. : Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis. Cell 101: 389-399, 2000.
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                                            Kommentare
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                        Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC. 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Lyophilized
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                                            Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            Konzentration
- 500 μg/mL
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                                            Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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                                            Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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                                            Handhabung
- Avoid repeated freezing and thawing.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
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    - 
                                            : "Effects of 5-hydroxy-4'-nitro-7-propionyloxy-genistein on inhibiting proliferation and invasion via activating reactive oxygen species in human ovarian cancer A2780/DDP cells."    in: Oncology letters, Vol. 15, Issue 4, pp. 5227-5235, (2018)         (PubMed).        
 : "Methacryloxylethyl Cetyl Ammonium Chloride Induces DNA Damage and Apoptosis in Human Dental Pulp Cells via Generation of Oxidative Stress." in: International journal of biological sciences, Vol. 12, Issue 5, pp. 580-93, (2017) (PubMed).
 : "Catalpol inhibits apoptosis in hydrogen peroxide-induced cardiac myocytes through a mitochondrial-dependent caspase pathway." in: Bioscience reports, Vol. 36, Issue 3, (2017) (PubMed).
 : "FABP4 reversed the regulation of leptin on mitochondrial fatty acid oxidation in mice adipocytes." in: Scientific reports, Vol. 5, pp. 13588, (2016) (PubMed).
 : "HOXB1 Is a Tumor Suppressor Gene Regulated by miR-3175 in Glioma." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142387, (2016) (PubMed).
 : "N-Acetyl Cysteine Depletes Reactive Oxygen Species and Prevents Dental Monomer-Induced Intrinsic Mitochondrial Apoptosis In Vitro in Human Dental Pulp Cells." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147858, (2016) (PubMed).
 : "Chinese herbal medicine Yougui Pill reduces exogenous glucocorticoid-induced apoptosis in anterior pituitary cells." in: Neural regeneration research, Vol. 11, Issue 12, pp. 1962-1968, (2016) (PubMed).
 : "Apoptosis-related protein expression in rabbits with blast brain injury following early hyperbaric oxygen therapy." in: Neural regeneration research, Vol. 7, Issue 17, pp. 1318-24, (2015) (PubMed).
 : "Protective Effects of Baicalin on A?????-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat." in: Cellular and molecular neurobiology, Vol. 35, Issue 5, pp. 623-32, (2015) (PubMed).
 : "Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina." in: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), Vol. 31, Issue 4, pp. 352-9, (2015) (PubMed).
 : "Forsythiaside protects against hydrogen peroxide-induced oxidative stress and apoptosis in PC12 cell." in: Neurochemical research, Vol. 40, Issue 1, pp. 27-35, (2015) (PubMed).
 : "Benzo(a)pyrene-7,8-diol-9,10-epoxide induced p53-independent necrosis via the mitochondria-associated pathway involving Bax and Bak activation." in: Human & experimental toxicology, Vol. 34, Issue 2, pp. 179-90, (2015) (PubMed).
 : "Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways." in: International journal of molecular medicine, Vol. 33, Issue 5, pp. 1298-304, (2014) (PubMed).
 : "Protective effects of phillyrin on H2O 2-induced oxidative stress and apoptosis in PC12 cells." in: Cellular and molecular neurobiology, Vol. 34, Issue 8, pp. 1165-73, (2014) (PubMed).
 : "Mono-(2-ethylhexyl) phthalate induces injury in human umbilical vein endothelial cells." in: PLoS ONE, Vol. 9, Issue 5, pp. e97607, (2014) (PubMed).
 : "Role of Bax/Bcl-2 family members in green tea polyphenol induced necroptosis of p53-deficient Hep3B cells." in: Tumour biology, Vol. 35, Issue 8, pp. 8065-75, (2014) (PubMed).
 : "Neuroprotective effect of tea polyphenols on oxyhemoglobin induced subarachnoid hemorrhage in mice." in: Oxidative medicine and cellular longevity, Vol. 2013, pp. 743938, (2014) (PubMed).
 : "Study of the mechanism of sonodynamic therapy in a rat glioma model." in: OncoTargets and therapy, Vol. 7, pp. 1801-10, (2014) (PubMed).
 : "Dexamethasone and A???-?? accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats." in: Behavioural brain research, Vol. 227, Issue 1, pp. 142-9, (2011) (PubMed).
 
 
- 
                                            : "Effects of 5-hydroxy-4'-nitro-7-propionyloxy-genistein on inhibiting proliferation and invasion via activating reactive oxygen species in human ovarian cancer A2780/DDP cells."    in: Oncology letters, Vol. 15, Issue 4, pp. 5227-5235, (2018)         (PubMed).        
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    - Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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                                            Andere Bezeichnung
- CYCS
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                                            Hintergrund
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                        Synonyms: Cytochrome c,CYCS,CYC, Tissue Specificity: Widely expressed, with highest levels in heart, brain, and skeletal muscle. . Background: Cytochrome C is located in the mitochondria of all aerobic cells and is involved in the electron transport system. Human cytochrome c has 104 amino acid residues and a molecular weight of 11,458 and is mapped to 7p15.2. Cytochrome c released from mitochondria has been proposed to be an essential component of an apoptotic pathway responsive to DNA damage and other forms of cell stress. And it has a role in different apoptotic signaling cascades. Sequence Similarities: Belongs to the cytochrome c family. 
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                                            Molekulargewicht
- 14 kDa
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                                            UniProt
- P99999
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                                            Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
 Target
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