MAFA Antikörper (Middle Region)

Produktnummer ABIN3043609

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch MAFA in WB. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für MAFA Antikörper (Middle Region) (ABIN3043609)

Target: MAFA (Transcription Factor MafA (MAFA))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAFA Antikörper

Bindungsspezifität: AA 136-167, Middle Region

Verwendungszweck: Anti-Transcription factor MafA MAFA Antibody

Sequenz: EDAVEALIGS GHHGAHHGAH HPAAAAAYEA FR

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Transcription factor MafA MAFA Antibody (ABIN3043609). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human MAFA, identical to the related mouse sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu MAFA

Target: MAFA (Transcription Factor MafA (MAFA))

Andere Bezeichnung: MAFA

Hintergrund:

Synonyms: Transcription factor MafA,Pancreatic beta-cell-specific transcriptional activator,Transcription factor RIPE3b1,V-maf musculoaponeurotic fibrosarcoma oncogene homolog A,MAFA,

Background: MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA plays a key role in coordinating and controlling the level of insulin gene expression in islet beta cells. It is located in 8q24.3. The intracellular domain of MAFA contains a single immunoreceptor tyrosine-based inhibitory motif (ITIM), which classifies MAFA as a member of an inhibitory receptor superfamily. The inhibitory capacity of MAFA is best defined in mast cells, where MAFA keeps in check the antigen-induced (i.e. Fc epsilon RI-induced) secretion ofinflammatory mediators.

Sequence Similarities: Belongs to the bZIP family. Maf subfamily.

Molekulargewicht: 37 kDa

Gen-ID: 389692

Pathways: Hormone Transport