PGK1 Antikörper (C-Term)

Produktnummer ABIN3043604

Produktdetails anti-PGK1 Antikörper

Target: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Bindungsspezifität: AA 312-337, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Phosphoglycerate kinase 1(PGK1) detection. Tested with WB in Human,Rat.

Sequenz: MGLDCGPESS KKYAEAVTRA KQIVWN

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Phosphoglycerate kinase 1(PGK1) detection. Tested with WB in Human,Rat.
Gene Name: phosphoglycerate kinase 1
Protein Name: Phosphoglycerate kinase 1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PGK1 (312-337aa MGLDCGPESSKKYAEAVTRAKQIVWN), different from the related mouse and rat sequences by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu PGK1

Target: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Andere Bezeichnung: PGK1 (PGK1 Produkte)

Synonyme: MIG10 antikoerper, PGKA antikoerper, Pgk-1 antikoerper, Pgk antikoerper, PGK antikoerper, wu:fd59b07 antikoerper, wu:fj36g06 antikoerper, zgc:56252 antikoerper, zgc:77899 antikoerper, PGK1 antikoerper, phosphoglycerate kinase 1 antikoerper, pgk2 antikoerper, pgka antikoerper, phosphoglycerate kinase 1 antikoerper, phosphoglycerate kinase 1 L homeolog antikoerper, PGK1 antikoerper, Pgk1 antikoerper, pgk1 antikoerper, LOC100348124 antikoerper, pgk1.L antikoerper

Hintergrund: PGK1 (Phosphoglycerate Kinase 1), also known as PGKA, is an enzyme that in humans is encoded by the PGK1 gene. The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.

Synonyms: Cell migration-inducing gene 10 protein antibody|MGC117307 antibody|MGC8947 antibody|MIG10 antibody|pgk1 antibody|PGK1_HUMAN antibody| PGKA antibody|Phosphoglycerate kinase 1 antibody|Primer recognition protein 2 antibody|PRP 2 antibody

Gen-ID: 5230

UniProt: P00558

Pathways: Cellular Glucan Metabolic Process