PFN1 Antikörper (C-Term)

Produktnummer ABIN3043603

Produktdetails anti-PFN1 Antikörper

Target: PFN1 (Profilin 1 (PFN1))

Bindungsspezifität: AA 116-140, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Profilin-1(PFN1) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: KEGVHGGLIN KKCYEMASHL RRSQY

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Profilin-1(PFN1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: profilin 1
Protein Name: Profilin-1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Profilin 1(116-140aa KEGVHGGLINKKCYEMASHLRRSQY), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Profilin 1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu PFN1

Target: PFN1 (Profilin 1 (PFN1))

Andere Bezeichnung: PFN1 (PFN1 Produkte)

Synonyme: GmPRO1 antikoerper, GmPRO2 antikoerper, PRO1 antikoerper, Profilin-1 antikoerper, profilin-1 antikoerper, profilin antikoerper, MGC130883 antikoerper, Profilin1 antikoerper, XProfilin1 antikoerper, sb:cb813 antikoerper, wu:fa91a03 antikoerper, ALS18 antikoerper, Pfn antikoerper, F6F22.21 antikoerper, F6F22_21 antikoerper, PFN1 antikoerper, PROFILIN 1 antikoerper, profilin 1 antikoerper, profilin antikoerper, profilin 1 antikoerper, profilin 1 L homeolog antikoerper, profilin homolog 1 antikoerper, Profilin-1 antikoerper, PRO2 antikoerper, PFN1 antikoerper, pfn1.L antikoerper, pfn1 antikoerper, Pfn1 antikoerper, PRF1 antikoerper, prf1 antikoerper, pfn-1 antikoerper

Hintergrund: Profilin-1 is a protein that in humans is encoded by the PFN1 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. PFN1 is mapped to 17p13.2. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. This gene is a 140-amino acid protein and major growth regulator of filamentous (F)-actin through its binding of monomeric (G)-actin. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.

Synonyms: Actin binding protein antibody|OTTHUMP00000125244 antibody|PFN 1 antibody|Pfn antibody|PFN1 antibody|PROF1_HUMAN antibody|Profilin I antibody|Profilin-1 antibody|Profilin1 antibody|ProfilinI antibody

Gen-ID: 5216

UniProt: P07737

Pathways: Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location