NK2 Homeobox 5 Antikörper (Middle Region)

Produktnummer ABIN3043568

Produktdetails anti-NK2 Homeobox 5 Antikörper

Target: NK2 Homeobox 5 (NKX2-5)

Bindungsspezifität: AA 103-132, Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NK2 Homeobox 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Homeobox protein Nkx-2.5(NKX2-5) detection. Tested with WB in Human,Mouse.

Sequenz: AKDPRAEKKE LCALQKAVEL EKTEADNAER

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Homeobox protein Nkx-2.5(NKX2-5) detection. Tested with WB in Human,Mouse.
Gene Name: NK2 homeobox 5
Protein Name: Homeobox protein Nkx-2.5

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Nkx2.5 (103-132aa AKDPRAEKKELCALQKAVELEKTEADNAER), different from the related mouse and rat sequences by five amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, The detection limit for Nkx2.5 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Andere Bezeichnung: NKX2-5 (NKX2-5 Produkte)

Hintergrund: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 directly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.

Synonyms: Cardiac-specific homeobox 1 antibody|Cardiac-specific homeobox antibody|CHNG5 antibody|CSX antibody|CSX1 antibody|FLJ52202 antibody|FLJ97166 antibody|FLJ97195 antibody|FLJ97197 antibody|FLJ99536 antibody|HLHS2 antibody|Homeobox protein CSX antibody|Homeobox protein NK-2 homolog E antibody|Homeobox protein Nkx 2.5 antibody|NK2 homeobox 5 antibody|NK2 transcription factor related locus 5 antibody|NK2 transcription factor related, locus 5 (Drosophila) antibody|Nkx2-5 antibody|NKX2.5 antibody|Nkx2E antibody|NKX4-1 antibody|Tinman paralog antibody|VSD3 antibody

Gen-ID: 1482

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development